Researchers completed Bacillus anthracis nanopore whole-genome sequencing from a human anthrax isolate hours after receipt. The de novo assembled genome showed no evidence of known antimicrobial resistance genes or introduced plasmid(s). Same-day genomic characterization enhances public health emergency response.
The US Department of Health and Human Services (HHS) as issued the first Project BioShield contract to fund the development needed to support the expanded use of an existing antibiotic to treat exposure to inhalational anthrax.
The US Defense Threat Reduction Agency’s Chemical and Biological Technologies Department (DTRA CB) has a new test that reduces the time needed to determine clearance decontamination for anthrax.
This report updates the 2009 recommendations from the US Centers for Disease Control and Prevention (CDC) Advisory Committee on Immunization Practices (ACIP) regarding use of anthrax vaccine in the United States. The report summarizes data on estimated efficacy in humans using a correlates of protection model and safety data and provides updated guidance for use of anthrax vaccine adsorbed for preexposure prophylaxis.
These revised anthrax vaccination recommendations apply to both pre- and post-exposure prophylaxis.
Anthrax is a rare but serious disease that’s caused by Bacillus Anthracis.
The Phase 1 clinical study is expected to begin enrollment this year and is being funded by the US National Institute of Allergy and Infectious Diseases (NIAID), an institute within the US National Institutes of Health (NIH).
A new study showing that removing the S-layer armor (a single layer of protein) that surrounds the bacterium Bacillus anthracis slows its growth and decreases its ability to cause disease. The researchers successfully applied small antibody fragments to control the assembly of the S-layer armor itself, which had an additional benefit in breaking down existing S-layers.
A mass vaccination of cattle is underway after an anthrax outbreak left one person dead in Kisumu, Kenya. County health officials are educating the public on the dangers of eating contaminated meat.
The first anthrax case of the year was confirmed in one captive antelope on a premises in Uvalde, TX.