Rinderpest, smallpox, and the imperative of destruction

This article touches on the United Kingdom’s Pirbright Institute to destroy all of its samples of Rinderpest, an eradicated virus. The institute’s technique of conducting whole genome sequencing of the samples and then destroying them provides a talking point on what facilities should do with samples of viruses that have been eradicated.

GAO-19-635T: Biodefense: The Nation Faces Long-Standing Challenges Related to Defending Against Biological Threats

This statement discusses US Government Accountability (GAO) reports issued from December 2009 through March 2019 on various biological threats and biodefense efforts. To conduct prior work, GAO reviewed biodefense reports, relevant presidential directives, laws, regulations, policies, strategic plans; surveyed states; and interviewed federal, state, and industry officials, among others.

Development and testing of a novel Killer-Rescue self-limiting gene drive system in Drosophila melanogaster

The killer rescue system is composed of an auto-regulated Gal4 Killer and a Gal4-activated Gal80 Rescue. This system may be used for population replacement in the pest Drosophila melanogaster and the disease transmitting Aedes aegypti mosquito.

Tough Decisions: Animal Mortality Disposal During a Disease Outbreak

Carcass disposal methods used during a disease outbreak include burial, composting, landfilling, and incineration. The use of these disposal methods may be limited during a large or widespread disease outbreak by biosecurity, transportation logistics, public perception, and environmental concerns.