Researchers developed a biodegradable synthetic lipid nanoparticle (which more easily penetrates the cell) to deliver CRISPR/Cas9. The nanoparticles encapsulate messenger RNA (mRNA) encoding Cas9. and once the contents of the nanoparticles are released the cell’s protein-making machinery creates Cas9 from the mRNA template.
Two biotechnology startups plan to use CRISPR to develop paper-based diagnostics that would not require the need for Polymerase chain reaction (PCR) or next-generation sequencing.
Researchers applied CRISPR and a new anti-retroviral therapy to eliminate HIV-1 in mice injected with human bone marrow.
As microbial geneticists start to utilize machine learning to analyze their data, microbiologist Nick Loman of the University of Birmingham cautions that scientists have plunged ahead with using artificial intelligence without fully understanding its benefits and limitations.
A new technique that mimics the way the body copies its own DNA may allow the creation of a gene in a single day.
Detection tools will only continue to improve, cheapen, and miniaturize leading to widely distributed sequencers in homes, offices, the broader biosphere, and even within human bodies.
The biotechnology safety regulations focus on preventing bioterrorism, activities that violate ethics, along with avoiding biosafety hazards.
As with biomedical applications, industrial applications center on chemicals, but chemicals produced by life forms that often have been tweaked or substantially altered. Thus, in a sense, synthetic biology also involves the creation of new life.
Nigeria is considering expanding the regulatory scope of its biosafety agency to address emerging technologies, such as gene editing, gene drives, and synthetic biology.
Researchers have created the largest synthetic genome ever made, with a smaller set of amino-acid-encoding codons than usual.