Variations of the genome editor CRISPR have wowed biology labs around the world over the past few years because they can precisely change single DNA bases. But such “base editors” can have a serious weakness. A pair of studies published this week shows that one kind of base editor causes many unwanted—and potentially dangerous— “off-target” genetic changes.
Advances in the field of biotechnology and synthetic biology are becoming increasingly accessible to actors wishing to do harm, while scientists and policymakers have become increasingly aware that the current regulatory framework may not be adequate.
Vaccines are risky or ineffective in people with compromised immune systems, they don’t even exist for several viral diseases. All of which gave scientists in half a dozen labs the same idea: Rescue one of the oldest biotechnologies with one of the newest — CRISPR.
Scientists have created an 'on' switch for CRISPR-Cas9 that allows it to be turned on in select cells only, specifically those that have a particular protein-cutting enzyme, or protease.
The very nature of gene drives, designed to force their genetically-modified characteristics into a population, could make their effects difficult or impossible to reverse.
The US Food and Drug Administration (FDA) plans to create a new office to improve the review of new medicines — one that will develop a standardized approach to using personalized medicine, digital data, and patients’ own reports, according to Commissioner Scott Gottlieb.
From genome editing to hacking the microbiome, advances in the life sciences and its associated technological revolution have already altered the biosecurity landscape.
This study highlights the changing safety and security landscape engendered by the emergence of new genome editing technologies, helps policy-makers and other stakeholders navigate this space, and illuminates broader trends in the life sciences that may impact the biosecurity landscape.
Computer-aided systems are helping researchers to create genetic circuits to order.
The 2018 6th International Conference on Agriculture and Biotechnology (ICABT 2018) will be held in Bangkok, Thailand,December 19-21, 2018. ICABT 2018 is sponsored by the Hong Kong Chemical, Biological & Environmental Engineering Society (HKCBEES) and Chulaongkorn University, Thailand.