‘The switch’ was supposed to be a major step toward eradicating polio. Now it’s a quandary

Three years ago, health officials phasied out a problematic component of the polio vaccine used in developing countries, and introduced a version that they hoped would put the world on a better footing to eradicate the disease. Now, some health officials are weighing whether “the switch,” as the process was known, needs to be reversed because they fear the new vaccine heightens the risk of the disease spreading indevelopin nations.

A Single Dose of Modified Vaccinia Ankara Expressing Lassa Virus-like Particles Protects Mice from Lethal Intra-cerebral Virus Challenge

The GEO-LM01 vaccine discussed in this paper provides two sources of viral antigens that mimic a natural viral infection promoting predominantly a balanced T cell response, which is critical for protection against Lassa virus infection.

Why the long-awaited Ebola vaccine won’t end the Congo outbreak

When current Ebola otbreak in the Democratic Republic of the Congo (DRC) began a year ago, the global stockpile of a new, promising vaccine was 300,000 doses. But as the virus continues to spread geographically, the supply of the new vaccine is dwindling, and is expected to run out before the outbreak ends.

Japanese Encephalitis Vaccine: Recommendations of the Advisory Committee on Immunization Practices

This report updates the 2010 recommendations from the US Centers for Disease Control and Prevention (CDC) Advisory Committee on Immunization Practices (ACIP) regarding prevention of Japanese encephalitis among US travelers and laboratory workers. The report summarizes the epidemiology of Japanese encephalitis, describes the US approved Japanese encephalitis vaccine, and provides recommendations for its use.