Researchers have developed “prime editing,” a true search-and-replace function for DNA.
Shape-shifting materials could be used to deliver drugs, and to create sentinels for almost any biological signal,
Researchers are using CRISPR/Cas9 to begin to treat cancer and blood disorders in human trials. Some of the diseases being researched are multiple myeloma and sickle-cell disease.
California passes a law that will require sellers of DIY gene editing kits to display a warning that states the kits are not intended for use on the buyer.
Doctors in the United States are using the CRISPR technique for the first time to treat Sickle Cell disease. The doctors are modifying the patients’ own bone marrow with CRISPR to get the marrow to produce a protein which is only made a short time following birth. The belief is the protein created will combat sickle cell.
Researchers developed a biodegradable synthetic lipid nanoparticle (which more easily penetrates the cell) to deliver CRISPR/Cas9. The nanoparticles encapsulate messenger RNA (mRNA) encoding Cas9. and once the contents of the nanoparticles are released the cell’s protein-making machinery creates Cas9 from the mRNA template.
Two biotechnology startups plan to use CRISPR to develop paper-based diagnostics that would not require the need for Polymerase chain reaction (PCR) or next-generation sequencing.
Researchers applied CRISPR and a new anti-retroviral therapy to eliminate HIV-1 in mice injected with human bone marrow.
What’s controversial about this research is that unlike gene therapies that alter the genes of adults to treat an inherited disease, this research attempts to alter germline DNA.
A Russian molecular biologist says he is planning to produce gene-edited babies, acting against the current scientific consensus that such experiments should be banned until an international ethical framework has agreed on the circumstances and safety measures.