According to an article in Nature Immunology researchers have used CRISPER Cas9 to discover a T-cell and its receptor that could find and kill a wide range of cancerous cells in the lab. While this discovery is the first of its kind, it is in the early stages and needs more research. There is potential in this discovery to identify new forms of cancer treatment.
Researchers developed the tool after discovering a jumping gene in Vibrio cholerae bacteria that could insert large genetic payloads in the genome without introducing DNA breaks.
A gene editing enzyme could be used to disable RNA viruses such as influenza or Ebola.
Crispr technology has not been able to insert new genes into DNA sequences well, but an update to the tool could fix this flaw.
Researchers have developed “prime editing,” a true search-and-replace function for DNA.
Shape-shifting materials could be used to deliver drugs, and to create sentinels for almost any biological signal,
Researchers are using CRISPR/Cas9 to begin to treat cancer and blood disorders in human trials. Some of the diseases being researched are multiple myeloma and sickle-cell disease.
California passes a law that will require sellers of DIY gene editing kits to display a warning that states the kits are not intended for use on the buyer.
Doctors in the United States are using the CRISPR technique for the first time to treat Sickle Cell disease. The doctors are modifying the patients’ own bone marrow with CRISPR to get the marrow to produce a protein which is only made a short time following birth. The belief is the protein created will combat sickle cell.
Researchers developed a biodegradable synthetic lipid nanoparticle (which more easily penetrates the cell) to deliver CRISPR/Cas9. The nanoparticles encapsulate messenger RNA (mRNA) encoding Cas9. and once the contents of the nanoparticles are released the cell’s protein-making machinery creates Cas9 from the mRNA template.