Backed by major funders, a group of scientists has created a platform to help the world's disease detectives.
By engineering cells with synthetic biology components, the research team has experimentally demonstrated a proof-of-concept device enabling robust and reliable information exchanges between electrical and biological (molecular) domains.
The app uses a smartphone's camera to measure a chemical reaction and determines a diagnosis in about an hour—and the simple, low-cost test can be performed in the world's most remote locations.
When patients presented with unexplained fever at Mwananyamala Hospital in Tanzania, scientists compared two genetic sequencing methods used to identify the potential viruses behind the illnesses: VirCapSeq-VERT and unbiased high-throughput sequencing.
The kit is designed to pick up a range of pathogens in humans, animals and plants, but it will first be used to detect malaria.
Scientists and engineers collaborated to develop a fully integrated, miniaturized semiconductor biochip with closed-tube detection chemistry to perform multiplexed nucleic acid amplification tests.
Diagnostic method exploits magnetic properties of parasite byproduct to detect all strains in low-resource environments.
Researchers designed a rapid assay for detection of Ebola virus using recombinase polymerase amplification.
New technique enables SHERLOCK to detect a virus directly in bodily fluids, eliminating a step that required lab equipment and expanding the platform’s potential to quickly and cheaply track pathogens anywhere in the world.
Researchers have created a shoebox-sized laboratory that can do blood testing in remote, low-resource settings, determining from a drop of blood whether a person has antibodies to specific infectious diseases.