The three patients were treated at separate hospitals in New York City. Samples from the three patients were resistant to all three classes of commonly prescribed antifungal drugs.
The World Health Organization conducted a study on drug-resistant HIV in 12 countries over the past 4 years and have found that more than 10% of adults being treated for HIV have developed a drug-resistant strain within these 12 countries.
Epidemiologic data and whole genome sequencing revealed a transmission of more than three years duration of New Delhi metallo-beta-lactamase-producing Klebsiella pneumoniae with antibiotic-resistant genes in a northern California hospital.
A British teenager has recovered after being the first person in the world to be given a genetically engineered virus to treat a drug-resistant infection.
The analysis of 1,521 samples taken from the edges of curtains, where they are touched most often, found 334 (22%) tested positive for multidrug-resistant organisms 9MDROs).
Scientists were able to determine that the strain that had sickened the patient had been in circulation in the hospital for at least a year prior to the patient's death, spreading between patients and throughout the wards of the hospital. It even traveled among the three campuses of the hospital, which were miles apart. The analysis also found that the isolates of the highly drug-resistant outbreak strain were carrying multiple antibiotic resistance genes and plasmids.
A prospective, observational study found that 39% of health care workers caring for patients on contact precautions for multidrug-resistant organisms (MDROs0 made multiple errors when doffing personal protective equipment (PPE), and that more than one-third were contaminated with an MDRO.
A large typhoid fever outbreak in Pakistan has resulted in 5,372 XDR Typhi cases reported during 2016–2018, and five travel-related cases in the United States.
Pakistan Health Authorities have reported an ongoing outbreak of extensively drug resistant typhoid fever that began in the Hyderabad district of Sindh province in November 2016. An increasing trend of typhoid fever cases caused by antimicrobial resistant strains of Salmonella enterica serovar Typhi (or S. Typhi) poses a notable public health concern.
Researchers at an Indian hospital have identified strains of hypervirulent, carbapenem-resistant Klebsiella pneumoniae associated with extremely high mortality rates. The findings represent the first report of a hypervirulent form of the drug-resistant pathogen in India.