The increasing incidence of multi-drug resistant organism infections has become a safety concern for patients across the continuum of patient care.
Azithromycin resistance in a S. Typhi pathogen would return developing countries to a pre-1948 scenario in which 15 percent of cases of typhoid fever end in fatality.
The guidance provides more than 100 recommendations on appropriate treatment for multidrug resistant (MDR) gram-negative bacterial (GNB) infections.
The Wellcome Trust is bringing together a new, international expert group, SEDRIC (Surveillance and Epidemiology of Drug-Resistant Infections Consortium) to improve our understanding and help reduce the global impact of drug-resistant infections.
Researchers who detected the drug-resistant typhoid cases confirmed that the newer type of water-borne disease was not responding to antibiotics.
The study found that antibiotic treatment of chronic infections can be optimized by targeting vulnerabilities of antibiotic-resistant pathogens.
Klebsiella bacteria, which cause significant morbidity and mortality, are becoming increasingly antimicrobial resistant.
Pathogenic fungi are becoming resistant to the drugs used to treat them.
Over the past seven years, this difficult to treat yeast has become widespread across several countries, causing a broad range of healthcare-associated invasive infections.