What’s controversial about this research is that unlike gene therapies that alter the genes of adults to treat an inherited disease, this research attempts to alter germline DNA.
Individual scientists and scientific societies have called for a moratorium on heritable genome editing in humans, but a moratorium raises the question of when does the moratorium end.
China had regulations against germline editing when the scientist edited two female embryos genes using CRISPR to make them (theoretically) resistant to HIV infection.
A Russian molecular biologist says he is planning to produce gene-edited babies, acting against the current scientific consensus that such experiments should be banned until an international ethical framework has agreed on the circumstances and safety measures.
Twin girls whose genomes were editied to make them resistant to HIV might have a shortened life expectancy as people with two disabled copies of the CCR5 gene — which protects against HIV infection — are 21 percent more likely to die before the age of 76 when compared to people with at least one working copy of the gene.
Researchers editied out a section of chicken DNA inside lab-grown cells which prevented the avian influenza virus from taking hold in the cells and replicating.
The US government and research scientists have identified a need for tools that can identify engineered organisms when they are mixed in with naturally occurring microorganisms.
According to lawyers, the pending regulation would mean that anyone who manipulates genes in humans is responsible for what happens to a person.
Nigeria is considering expanding the regulatory scope of its biosafety agency to address emerging technologies, such as gene editing, gene drives, and synthetic biology.
A research project that used CRISPR to make cassava resistant to mosaic virus instead allowed the virus to mutate and be passed down to the next generation.