The very nature of gene drives, designed to force their genetically-modified characteristics into a population, could make their effects difficult or impossible to reverse.
The goal of this Keystone Symposia conference is to bring together those developing and studying genome engineering tools with groups who are applying them to build new disease models, identify disease mechanisms and drug targets, and develop cell-based therapeutics and genetic medicines. In addition to covering engineering of human and animal cells, this conference will also highlight the emerging field of genome engineering to identify new anti-microbial and anti-viral drugs and applications toward next-generation antibiotics.
In calling for standards for producing such ‘CRISPR-edited’ babies, leaders have shunted aside a crucial and as-yet-unanswered question: whether it is (or can ever be) acceptable to genetically engineer children by introducing changes that they will pass on to their own offspring.
According to the Wall Street Journal, a number of cancer patients in China underwent gene modification with the gene-editing tool, CRISPR-Cas9, but some scientists who administered the trial have neglected to keep track of patients who underwent gene-editing treatment.
From genome editing to hacking the microbiome, advances in the life sciences and its associated technological revolution have already altered the biosecurity landscape.
By preventing bioengineered microalgae from growing outside the lab, researchers have reduced the risk of the genetically modified organisms escaping into the wild.
The claims from He Jiankui that he has used gene editing to produce twin girls demand action. A new registry of research is a good start.
Scientists say there's no certain way to stop someone intent on monkeying with DNA, no matter what laws or standards are in place.
The genome editing of germ cells or early embryos is still in the stage of basic research, and its safety and validity need to be fully evaluated.
Mankind’s newfound ability to edit germline codes will soon be widely available. We will also be able to extend the palette of naturally available amino acids for molecular assembly. The US needs a policy framework that defines and addresses the five key decisions that will determine whether we can leverage the benefits and simultaneously defend against attacks.