According to terms of the agreement, Profectus will receive $4.3 million from the Coalition for Epidemic Preparedness Innovations (CEPI) to support the first phase of its Lassa vaccine project, with an option to invest up to a total of $36 million over five years, which could cover procuring vaccine for stockpiling.
The Nigeria Centre for Disease Control (NCDC) has confirmed nine new cases of Lassa fever with two deaths, in one week, including the first confirmed case in Enugu State.
The International AIDS Vaccine Initiative (IAVI) has entered into a license agreement with the Public Health Agency of Canada (PHAC) toward advancing development, regulatory approval, and supply of a new vaccine candidate against Lassa fever virus
The Edo State Commissioner for Health has reported new cases of Lassa fever in Esan North-East, Esan Central, Etsako East and other local government areas.
The Federal Government of Nigeria says 115 people from across 21 states have died of Lassa fever since the disease outbreak was confirmed in January this year.
Researchers have uncovered a protein enabling the replication of arenaviruses, pathogens carried by rodents that can infect humans and cause lethal hemorrhagic fevers.
Cases of Lassa fever are on the increase in the Lassa belt (Bong, Nimba, and Grand Bassa Counties).
The current Lassa fever outbreak in Nigeria has killed two people in Plateau and Edo with six new confirmed cases from Edo (four), Ondo (one) and Plateau (one).
One key lesson learnt from the investigation was that the confirmed cases were mainly primary cases; hence the needs to focus on measures of breaking the chain of transmission in the animal-man interphase during Lassa fever epidemic preparedness and response.
Since the beginning of January, a total of 112 suspected Lassa fever cases have been reported across Liberia. Eighteen have been confirmed positive by RT-PCR (Nimba-7, Montserrado-3, Bong-4 Margibi-2, and Grand Bassa-2.