Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection

Plasmodium species produce an ortholog of the cytokine macrophage migration inhibitory factor, PMIF, which modulates the host inflammatory response to malaria. Using a novel RNA replicon-based vaccine, researchers showed the impact of PMIF immunoneutralization on the host response.

Genomic Epidemiology of Malaria

This multidisciplinary meeting provides a forum for malaria scientists and clinicians focused on understanding the clinical and biological consequences of genome variation in malaria-exposed populations. The conference will bring researchers from across the globe working on various aspects of human, parasite and mosquito genetics together to focus on how new biological insights can be used to control malaria.