The study investigated risk factors for Middle East respiratory syndrome (MERS) seropositivity in animal market and slaughterhouse workers at a site previously associated with zoonotic transmission of MERS. Given the large number of camels present, including many young camels, and the mixing of camels from multiple sources, this site probably facilitates MERS transmission among camels. Results demonstrated a relatively high MERS seroprevalence in workers at this site, ranging from six percent to 19 percent at each round across all occupations.
Researchers made two versions of a potential vaccine and evaluated their effectiveness and safety in mice that were genetically altered to have more human-like immune responses. After the mice were vaccinated and then infected with Middle East respiratory syndrome (MERS), both vaccines protected the mice against clinical signs of disease and death.
The Saudi Ministry of Health is reporting two more Middle East respiratory syndrome (MERS) cases from Al Khafji , both of which are currently listed as `under investigation'. As with the previous four cases, all are older males.
Scientists have isolated therapeutic antibodies from healthy volunteers exposed to the Ebola vaccine but not Ebola virus itself, suggesting that protective therapies could be developed from people who are disease-free.
Middle East respiratory syndrome coronavirus (MERS-CoV) shedding and antibody responses are not fully understood, particularly in relation to underlying medical conditions, clinical manifestations, and mortality.
The World Health Organization (WHO) Monday, March 4, detailed eight more Middle East respiratory syndrome (MERS) cases in Oman, some of which—including two fatalities—are part of a second illness cluster, and others apparently part of an earlier cluster.
Research found that vaccination with an adjuvanted Middle East respiratory syndrome (MERS) Spike protein subunit vaccine confers complete protection from MERS disease in alpaca and results in reduced and delayed viral shedding in the upper airways of dromedary camels. Together, these data indicate that induction of robust neutralizing humoral immune responses by vaccination of naïve animals reduces shedding that potentially could diminish the risk of zoonotic transmission.
Nine healthcare workers are among the 39 Middle East respiratory syndrome (MERS) patients identified in a hospital-based outbreak of the virus in Wadi ad-Dawasir, and according to the World Health Organization's (WHO) technical lead the outbreak features both human-to-human transmission patterns and spread from animals.
The review compiled and analyzed all published data on Middle East respiratory syndrome (MERS) in the global camel population to provide an overview of current knowledge on the distribution, spread and risk factors of infections in dromedary camels.
Monday, February 25, the Saudi Ministry of Health (MOH) announced the 50th Middle East respiratory syndrome (MERS) case since January 29th in the town of Wadi Aldwasir (pop 106,000), located about 500 km south of Riyadh.