The World Health Organization (WHO) reported 14 Middle East respiratory syndrome (MERS) cases in May.
Dromedary camels play a significant part in the circulation and the zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Researchers demonstrated that Bactrian camels are also susceptible to MERS-CoV infection and shed large quantities of infectious virus in nasal secretions.
The study found the research, case fatality rate was 30.5 percent for males and 25.8 percent for females.
The study investigated risk factors for Middle East respiratory syndrome (MERS) seropositivity in animal market and slaughterhouse workers at a site previously associated with zoonotic transmission of MERS. Given the large number of camels present, including many young camels, and the mixing of camels from multiple sources, this site probably facilitates MERS transmission among camels. Results demonstrated a relatively high MERS seroprevalence in workers at this site, ranging from six percent to 19 percent at each round across all occupations.
Researchers made two versions of a potential vaccine and evaluated their effectiveness and safety in mice that were genetically altered to have more human-like immune responses. After the mice were vaccinated and then infected with Middle East respiratory syndrome (MERS), both vaccines protected the mice against clinical signs of disease and death.
The Saudi Ministry of Health is reporting two more Middle East respiratory syndrome (MERS) cases from Al Khafji , both of which are currently listed as `under investigation'. As with the previous four cases, all are older males.
Middle East respiratory syndrome coronavirus (MERS-CoV) shedding and antibody responses are not fully understood, particularly in relation to underlying medical conditions, clinical manifestations, and mortality.
The country has now reported 102 cases of Middle East respiratory syndrome (MERS) since the first of the year, of which 57 are linked to the outbreak in Wadi ad-Dawasir, most of which are linked to healthcare exposure, with some related to contact with camels.
The World Health Organization (WHO) Monday, March 4, detailed eight more Middle East respiratory syndrome (MERS) cases in Oman, some of which—including two fatalities—are part of a second illness cluster, and others apparently part of an earlier cluster.
Research found that vaccination with an adjuvanted Middle East respiratory syndrome (MERS) Spike protein subunit vaccine confers complete protection from MERS disease in alpaca and results in reduced and delayed viral shedding in the upper airways of dromedary camels. Together, these data indicate that induction of robust neutralizing humoral immune responses by vaccination of naïve animals reduces shedding that potentially could diminish the risk of zoonotic transmission.