Rapid Nanopore Whole-Genome Sequencing for Anthrax Emergency Preparedness

Researchers completed Bacillus anthracis nanopore whole-genome sequencing from a human anthrax isolate hours after receipt. The de novo assembled genome showed no evidence of known antimicrobial resistance genes or introduced plasmid(s). Same-day genomic characterization enhances public health emergency response.

Scaling up preparedness for high-threat pathogen outbreaks in Kyrgyzstan

Epidemiologists, veterinarians, and laboratory technicians from across Kyrgyzstan participated in a five-day specialized training to deepen their knowledge on existing diagnostic methods and procedures to prevent outbreaks caused by high-threat pathogens – such as anthrax, cholera, rabies, and brucellosis.

Research Team Creates Bacterial Sensor Modeled After the Immune System

Los Alamos National Laboratory (LANL) researchers designed a Universal Bacterial Sensor—modeled after the human innate immune system—that mimics the biological recognition of all categories of bacterial pathogens. Requiring less than a drop of blood, it detects all pathogens without prior knowledge of what they might be, before symptom onset.

The Problem With Big DNA

As sequencing becomes more common, the number of publicly available bacterial and viral genomes has doubled. At the rate this work is going, within a few years multiple millions of searchable pathogen genomes will be available—a library of DNA and disease, spread the world over.