A Hexaplex PCR Assay Developed for Simultaneous Detection of Bacillus anthracis and Yersinia pestis and Distinguish Their Virulence Levels Tested on Vietnamese Samples

Current diagnostic approaches for Bacillus anthracis and Yersinia pestis have limited sensitivity, are time-consuming, and require the use of skilled personnel in biosafety level 3 laboratories.

Living with plague: Lessons from the Soviet Union’s antiplague system

During the 20th century, an extensive plague-eradication effort was initiated to enable changes in land use in the former Soviet Union. Despite expending tremendous resources in its attempt to eradicate plague, the Soviets abandoned the goal of eradication in favor of plague control linked with developing basic knowledge of plague ecology.

A Bacteriophage T4 Nanoparticle-Based Dual Vaccine against Anthrax and Plague

Two doses of the vaccine provided complete protection against both inhalational anthrax and pneumonic plague in animal models. Further, results establish the T4 nanoparticle as a novel platform to develop multivalent vaccines against pathogens of high public health significance.