Research found that vaccination with an adjuvanted Middle East respiratory syndrome (MERS) Spike protein subunit vaccine confers complete protection from MERS disease in alpaca and results in reduced and delayed viral shedding in the upper airways of dromedary camels. Together, these data indicate that induction of robust neutralizing humoral immune responses by vaccination of naïve animals reduces shedding that potentially could diminish the risk of zoonotic transmission.
The review compiled and analyzed all published data on Middle East respiratory syndrome (MERS) in the global camel population to provide an overview of current knowledge on the distribution, spread and risk factors of infections in dromedary camels.
The researchers found that the inflammation sensor that normally triggers the body's response to fight off stress and infection, a protein called NLRP3, barely reacts in bats compared to humans and mice, even in the presence of high viral loads.
Zika virus (ZIKV) is transmitted to humans by Aedes sp. mosquitoes, yet little is known about its enzootic cycle in which transmission is thought to occur between arboreal Aedes sp. mosquitos and non-human primates.
Researchers surveilled camels in Egypt, Tunisia, and Senegal to include other domestic mammalian species in contact with infected camels.
Although the bat was found in Liberia, the country has not had any human cases of Ebola since 2016, and the bat was not associated with any illness in people.
Scientists will conduct research in two national parks in southern Africa that differ in the timing and severity of anthrax outbreaks. They will investigate the roles of host, pathogen and environment to understand how the pathogen-host interaction evolves and contributes to the differences in anthrax occurrences in the two study areas.
Ross River virus is Australia’s most common mosquito-borne disease. It infects around 4,000 people a year.
By running data on flavivirus-positive species through a machine-learning model of known mammal and bird species, scientists from the University of California, Davis (UC Davis) believe they’ve honed-in on those animals most likely to host future flaviviruses.
Although rare, zoonotic diseases such as Methicillin –resistant Staphylococcus aureus (MRSA) have been shown to be transmitted from humans to horses and horses to humans putting those that work with horses at a higher risk.