A Saskatoon, Canada organization has been given federal approval to develop a vaccine for deadly African Swine Fever.
This report updates the 2009 recommendations from the US Centers for Disease Control and Prevention (CDC) Advisory Committee on Immunization Practices (ACIP) regarding use of anthrax vaccine in the United States. The report summarizes data on estimated efficacy in humans using a correlates of protection model and safety data and provides updated guidance for use of anthrax vaccine adsorbed for preexposure prophylaxis.
These revised anthrax vaccination recommendations apply to both pre- and post-exposure prophylaxis.
A single dose of the typhoid conjugate vaccine was immunogenic and effective in reducing Salmonella Typhi bacteremia in children nine months to 16 years of age.
Despite significant gains in understanding of Shigella infection, it remains unknown how the bacteria initiate contact with the colonic epithelium. This research identified conditions that mimic some features of gastrointestinal transit and that enable Shigella to express adherence structural genes.
Researchers demonstrated a new strategy for engineering a live bacterial vaccine that has been rationally-designed to optimize both protection and diagnostic compatibility.
Pakistan began vaccinating millions of children against typhoid on Friday, November 15, in response to a drug-resistant superbug outbreak of the fever that has already infected 11,000 people since 2016 and risks spreading internationally.
Researchers assigned 440 participants to receive two doses of MVA followed by one dose of the established replicating-vaccinia vaccine ACAM2000 (the MVA group) or to receive one dose of ACAM2000 (the ACAM2000-only group). No safety concerns associated with the MVA vaccine were identified, and immune responses and attenuation of the major cutaneous reaction suggest the MVA vaccine protected against variola infection.
The US Defense Threat Reduction Agency (DTRA) has awarded $35.7 million dollars to develop a recombinant vesicular stomatitis virus vector Marburg virus vaccine.
The US Government is funding a project to develop a vaccine for a pneumonia-like disease. The vaccine was effective in a one-month study with mice that found it prevented those treated from contracting melioidosis, a disease caused by contact with bacteria typically found in Puerto Rico, Southeast Asia, and Australia.