Researchers develop new vaccine against deadly Middle East Respiratory Syndrome

Researchers made two versions of a potential vaccine and evaluated their effectiveness and safety in mice that were genetically altered to have more human-like immune responses. After the mice were vaccinated and then infected with Middle East respiratory syndrome (MERS), both vaccines protected the mice against clinical signs of disease and death.

Homeland Security Ramps Up African Swine Fever Vaccine Research

The Department of Homeland Security Science and Technology Directorate (S&T) has been intensifying African swine fever (ASF) vaccine research efforts since November in collaboration with the USDA. The African Swine Fever Task Force was created, based out of S&T’s Plum Island Animal Disease Center (PIADC), to tackle this threat to the swine industry.

HHS’ BARDA Funds Its First Marburg Virus Vaccine Development

To increase national health security against biothreats and protect public health, the US Department of Health and Human Services (HHS) will partner with Public Health Vaccines LLC of Cambridge, Massachusetts, to develop a potential vaccine against Marburg virus. No licensed vaccine for this virus exists today.

Efficacy of an Adjuvanted Middle East Respiratory Syndrome Coronavirus Spike Protein Vaccine in Dromedary Camels and Alpacas

Research found that vaccination with an adjuvanted Middle East respiratory syndrome (MERS) Spike protein subunit vaccine confers complete protection from MERS disease in alpaca and results in reduced and delayed viral shedding in the upper airways of dromedary camels. Together, these data indicate that induction of robust neutralizing humoral immune responses by vaccination of naïve animals reduces shedding that potentially could diminish the risk of zoonotic transmission.