The theory holds that one immunization, given properly, can protect against many diseases besides its target.
This paper discusses scientific and policy issues related to vaccine platforms, and how they are understood in government, academia, and industry.
Vaccines are risky or ineffective in people with compromised immune systems, they don’t even exist for several viral diseases. All of which gave scientists in half a dozen labs the same idea: Rescue one of the oldest biotechnologies with one of the newest — CRISPR.
To develop the oral vaccine, the researchers coated magnesium micromotors with red blood cell membranes that displayed the Staphylococcal α-toxin, along with a layer of chitosan to help them stick to the intestinal mucus. Then, they added an enteric coating that protects drugs from the acidic conditions of the stomach.
An innovative new technology developed by Fraunhofer researchers will use electron beams to produce inactivated vaccines quickly, reproducibly and without the use of chemicals.
The $8.4million project will develop technology to rapidly develop vaccines against known pathogens - such as flu, and unknown pathogens, called Disease X. The project will create a so-called self-amplifying RNA (saRNA) vaccine platform.
In addition to an Ebola vaccine, the Coalition for Epidemic Preparedness Innovations is currently funding the development of vaccines for Lassa fever, Middle East respiratory syndrome, Nipah virus, and coronavirus at the Jenner Institute; and by using the same technology as the Ebola vaccine — called viral vectors — researchers can significantly reduce the time it takes to develop vaccines.
Recent research outlines how near-infrared spectroscopy could be used to make cell-culture-based flu vaccine manufacturing faster and more efficient.
Researchers are developing methods with which viruses for vaccines can be replicated in significantly higher concentrations than before. The researchers produce the pathogens in cell cultures in small bioreactors.
The first bout of flu may determine how a person fares during the next pandemic. That’s why scientists are trying to understand immunologic imprinting.