The new tools will allow the team to test for Zika RNA in the field in 30 minutes.
The Puerto Rican government reports there have been around 10 cases of Zika reported in four-week periods since April, which is down from over 8,000 cases reported in four-week periods during the same time period in 2016.
Researchers have confirmed through tests that the naturally occurring compounds halted the virus and stopped it replicating without damage to host mammalian cells.
Strategic releases could transform mosquito populations and virus transmission across cities.
The three infections, found during routine lab surveillance, were all from Bapunagar.
Researchers believe that Zika may have started transmission in Miami as many as 40 times, with mosquito control efforts managing to limit spread.
The Singapore Zika outbreak demonstrated the ease with which Zika virus can be introduced and spread despite good baseline vector control.
Between 2007 and 2016, Zika mutated to more easily board biting mosquitoes.
Brazil has been under a state of emergency for the Zika virus for the last eighteen months.
Walter Reed Army Institute of Research's (WRAIR) inactivated flavivirus vaccine platform was the same technology used to create its Japanese encephalitis vaccine.